VP, Clinical Development with an Oncology Biotech – San Diego, CA

Position Overview

JRG Partners is exclusively representing a pioneering, clinical-stage oncology biotechnology company located in San Diego, CA – a vibrant hub for life sciences. This role is a career-defining opportunity for a visionary Vice President (VP) of Clinical Development. You will own the design, execution, and interpretation of clinical trials for the entire oncology portfolio, reporting directly to the Chief Medical Officer (CMO). In this transformative leadership role, you will provide medical and scientific guidance, build and mentor a high-performing clinical team, and serve as the primary clinical spokesperson with regulatory agencies and external stakeholders.

Key Responsibilities

• Develop and implement comprehensive, global clinical development plans for all oncology assets, from first-in-human studies through registration and post-marketing commitments.
• Oversee the design, execution, and management of clinical trials (Phase I-IV), including protocol development, site selection, patient recruitment, and adherence to GCP, ICH, and global standards.
• Build, lead, and mentor a world-class clinical development team, fostering a culture of innovation, scientific rigor, and patient safety.
• Act as the primary clinical representative with regulatory agencies such as the FDA and EMA, leading regulatory submissions including INDs, NDAs, and BLAs.
• Oversee the analysis, interpretation, and communication of clinical trial data, ensuring timely dissemination of study results through publications and presentations.
• Collaborate with cross-functional teams in Research, Preclinical Development, Regulatory Affairs, Biostatistics, CMC, and Commercial to integrate clinical strategies with overall drug development.
• Engage with Key Opinion Leaders (KOLs), academic partners, and patient advocacy groups, and chair clinical advisory boards to guide program execution.
• Ensure patient safety by overseeing medical monitoring and collaborating with the safety/pharmacovigilance team to maintain robust risk management plans.
• Manage the annual clinical development budget with keen oversight on resource allocation to meet milestone targets.

Required Qualifications

• An M.D. is required; an advanced degree (PhD, MPH) is a plus. Board Certification in Medical Oncology or Hematology/Oncology is strongly preferred.
• Minimum of 12-15 years of progressive experience in clinical development within the biotech or pharmaceutical industry, including at least 7 years in a leadership role managing clinical programs.
• Deep expertise in oncology with a broad understanding of various tumor types and therapeutic modalities (e.g., small molecules, biologics, cell therapy, immuno-oncology).
• Demonstrated success in advancing clinical programs from early-phase (Phase I) through late-stage (Phase III) and achieving regulatory approvals (NDA/BLA).
• Extensive experience working with global health authorities (FDA, EMA) and a thorough understanding of global regulatory requirements.
• Exceptional leadership, communication, and strategic thinking skills with the ability to mentor teams and influence key corporate decisions.
• A 'roll-up-your-sleeves' mindset and the ability to thrive in a fast-paced, entrepreneurial environment.

Benefits & Perks

• Compensation: A competitive base salary and an attractive annual performance-based bonus.
• Equity: A significant equity stake through stock options, offering long-term wealth creation.
• Insurance: Comprehensive health, dental, and vision coverage for you and your dependents.
• Retirement: A robust 401(k) plan with a generous company match.
• Paid Time Off: Generous PTO including vacation, sick leave, and paid company holidays.
• Relocation: Assistance for exceptional candidates relocating to the San Diego area.
• Professional Development: Support for conference attendance and continued education.
• Opportunity to work in a dynamic, mission-driven culture dedicated to transforming cancer treatment.