Principal Investigator (Assistant, Associate or Full Staff) - Cardiovascular and Metabolic Sciences

Position Overview

The Department of Cardiovascular and Metabolic Sciences at Cleveland Clinic, chaired by Dr. Stanley Hazen, MD, PhD, is seeking innovative investigators to advance research in cardiovascular diseases. Using multidisciplinary approaches, candidates will conduct mechanistic investigations—ranging from cellular and molecular studies to computational, animal, and human clinical research—with a focus on cardio-metabolism, vascular biology, atherosclerosis, thrombosis, arrhythmia, and heart failure. Appointments will be at the Assistant, Associate, or Full Staff level, with potential joint appointments for physician‐scientists.

Key Responsibilities

• Leverage existing clinical infrastructure and research expertise to drive programmatic efforts in cutting‑edge cardiovascular research.
• Conduct rigorous mechanistic investigations using diverse experimental systems.
• Collaborate with interdisciplinary teams across the Lerner Research Institute and partner with over 25 Departments and Centers.
• Participate in academic programs and contribute to the excellence and diversity of the academic community.

Required Qualifications

• Demonstrated expertise in mechanistic investigations in cardiovascular and metabolic sciences.
• Experience with experimental systems such as cellular, molecular, computational, animal models, and/or human clinical studies.
• Proven track record of innovative research and competitive funding (e.g., NIH funding is highly desirable).
• Ability to thrive in a collaborative, multidisciplinary research environment.

Preferred Qualifications

• Expertise in cardio‑metabolism, vascular biology, atherosclerosis, thrombosis, arrhythmia, or heart failure.
• For physician‑scientists, a willingness to accept joint appointments in clinical institutes is an advantage.
• Demonstrated ability to secure and manage competitive research funding.

Benefits & Perks

• Access to outstanding facilities, state‑of‑the‑art core laboratories, and generous start‑up funds.
• Ongoing operational support within a highly collaborative research environment.
• Comprehensive benefits package including healthcare, dental, vision, retirement, and more.
• Opportunities for career advancement and collaboration with Case Western Reserve University School of Medicine.
• Location benefits: Enjoy the vibrant community and quality of life in Cleveland, Northeast Ohio.
• Compensation: Pay Range – Minimum: $130,000; Maximum: $300,000. (Excludes the value of the comprehensive benefits package.)

Application & Additional Information

Interested candidates must submit a complete curriculum vitae, a brief statement of research interests, and names of three references by email to Alyssa Carmigiano at carmiga@ccf.org. Please note that application processing will be delayed if the CV is not included.

Cleveland Clinic is committed to delivering outstanding patient care and creating a fulfilling work environment. Additional requirements include compliance with Cleveland Clinic’s influenza prevention program. We are an equal employment opportunity employer and maintain a smoke-/drug-free environment.