Senior Scientist – Manufacturing Science

Position Overview

At Lilly, we unite caring with discovery to make life better for people around the world. As a global healthcare leader headquartered in Indianapolis, Indiana, we work to discover and deliver life-changing medicines, improve disease management, and give back to our communities. In this role, the Senior Scientist – Manufacturing Science is responsible for providing the technical support required to ensure the reliable and compliant manufacture of the API External Manufacturing (API EM) portfolio, which includes raw materials, intermediates, enzymes, and bulk drug substances. The successful candidate will execute technical projects—ranging from experimental work to data analysis—to improve process control, yield, purity, and productivity while independently setting up and executing various laboratory-scale experiments.

Key Responsibilities

• Understand the scientific principles required for manufacturing intermediates and bulk drug substances, including the interaction between chemistry and equipment.
• Execute technical projects (experimental, modeling, and/or production data analysis) to optimize process control, yield, purity, and productivity.
• Prepare and support the drafting of technical documents such as reports, change controls, regulatory submissions, deviation investigations, validation protocols, and procedures.
• Develop and monitor real-time metrics to assess process variability and capability.
• Document the state of validation (process and cleaning) with data that evaluate manufacturing process capability.
• Ensure that instructions, procedures, and process flow diagrams accurately reflect the process and control strategy.
• Provide support to internal, joint process teams as well as global and local PLOT teams.
• Design and execute chemical reactions and experiments independently, ensuring clear objectives and proper documentation.
• Utilize sound laboratory practices and adhere to CHP requirements.
• Write clear and comprehensive technical reports and documents.

Required Qualifications

• Experience Required: 3+ years of relevant industrial experience in disciplines such as API Manufacturing, TS/MS, Quality Control, Quality Assurance, or Development.
• Education: Bachelors or equivalent in scientific disciplines such as Biochemistry, Organic Chemistry, Chemical Engineering, Physical Chemistry, Bioanalytical Chemistry, or Analytical Chemistry.
• Willingness to adhere to safety protocols including the use of appropriate PPE in manufacturing areas and the ability to travel domestically and internationally (up to 20%).

Preferred Qualifications

• Demonstrated basic knowledge in small molecule API Manufacturing.
• Familiarity with a cGMP manufacturing environment and terminology.
• Excellent analytical, interpersonal, written, and oral communication skills.
• Ability to work both independently and collaboratively as part of a team.
• Strong capability to prioritize activities with good judgment and flexibility.

Benefits & Perks

• Compensation: $64,500 - $167,200
• Benefits: Comprehensive benefits program including eligibility for a company-sponsored 401(k), pension, vacation, medical, dental, vision, prescription drug coverage, flexible spending accounts, life insurance, employee assistance programs, wellness benefits, and bonus opportunities based on performance.